Florence (Firenze) is the birthplace of the Renaissance and a city brimming with extraordinary art, rich history, and captivating architecture. This enchanting Italian city situated within the heart of Tuscany is a dream destination for travelers who appreciate culture and crave the opportunity to explore world-famous landmarks while connecting with centuries of artistic innovation.
Having lived in Florence and returned many times since, I’ve discovered the city’s iconic attractions and countless hidden gems. Trust me when I say every cobblestone street, medieval piazza, and Renaissance palazzo tells a story worth hearing. With this carefully crafted weekend itinerary, you’ll experience Florence’s must-see landmarks and uncover its magical, lesser-known corners in just two days.
As you venture through the city’s captivating streets, don’t forget to pause and savor the exquisite flavors of Italian cuisine. From mouthwatering gelato to rich espresso, your taste buds will celebrate while you refuel for your next Florentine adventure. Let’s embark on this journey together and create memories in Florence that will last a lifetime!
Weekend in Florence: Quick Reference Guide
- Must-See Attractions: Duomo (Florence Cathedral), Uffizi Gallery, Accademia Gallery (Michelangelo’s David), Ponte Vecchio, Piazzale Michelangelo
- Best Time to Visit: May-June and September-October for pleasant weather and fewer crowds
- Getting Around: Florence’s historic center is best explored on foot; public transit available for longer distances
- Where to Stay: Santa Maria Novella (convenient), Oltrarno (authentic), Duomo area (central)
- Don’t Miss: Sunset views from Piazzale Michelangelo, authentic Tuscan cuisine, gelato from local artisanal shops
Overview of Florence

Picture yourself strolling through the streets of Florence, a city with a rich history, breathtaking Renaissance architecture, and fascinating cultural treasures at every turn. As the capital of Tuscany in central Italy, Florence has long been an influential center of trade, finance, art, and culture that shaped European history.
The city’s architectural jewels include the magnificent Florence Cathedral (Duomo) with Brunelleschi’s innovative dome, the medieval Ponte Vecchio bridge spanning the Arno River, and world-class art museums such as the renowned Uffizi Gallery, filled with priceless masterpieces by Botticelli, Leonardo da Vinci, and Michelangelo.
Florence’s impact on Italy and Europe cannot be overstated. Founded by the Romans in 59 BC, Florence later became a crucial European trade and finance center during the medieval period. Its influence grew even more as it became the birthplace of the Renaissance when art, science, culture, politics, and economics flourished under the patronage of the powerful Medici family, who left an indelible mark on the city’s museums, palaces, and churches.
During the Renaissance, Florence attracted the most brilliant minds and talented artists. The city was home to architectural genius Filippo Brunelleschi, sculptor Donatello, and painters like Botticelli and Fra Angelico. Both Leonardo da Vinci and Michelangelo developed their extraordinary talents in Florentine workshops.
Their collective genius transformed not just Florence but the entire course of Western art and thought—no wonder the Historic Centre of Florence was designated a UNESCO World Heritage Site in 1982.
Even the European language and commerce were deeply influenced by Florence. The local Florentine dialect, which formed the foundation of the modern Italian language, spread throughout Italy through literary masterpieces by Dante, Petrarch, and Boccaccio. Florentine banks and merchants facilitated trade and finance across the continent, and the gold florin currency became a standard of wealth and power.
How Many Days Do You Need in Florence?

Deciding how many days you need in Florence will depend on your travel style and what you want to accomplish during your visit. I recommend two solid days for first-time visitors to experience the city’s major highlights. This includes exploring the magnificent Uffizi Gallery, admiring the stunning Duomo, standing in awe before Michelangelo’s David, strolling across the historic Ponte Vecchio, and savoring sunset views from breathtaking vantage points.
With only a weekend (48 hours), you must plan your itinerary carefully to maximize your time. Be prepared to stay on your feet and move efficiently between attractions. Your efforts will be rewarded as you immerse yourself in the beauty of Florence, taking in Renaissance masterpieces and Florentine culture.
If you desire a more relaxed pace or want to dive deeper into the city’s rich artistic heritage, extending your stay to 3 or 4 days is ideal.
With additional time, you can explore lesser-known gems such as the Convent of San Marco with its ethereal Fra Angelico frescoes, the Basilica of San Lorenzo with its Medici connections, or even visit neighboring Tuscan towns like Siena or Pisa for a day trip from Florence. Check out this comprehensive Italy trip planner for inspiration on longer Italian itineraries.
Photographers and food enthusiasts may be inclined to spend even longer in Florence. The city offers countless visual delights and culinary experiences, from early morning light on ancient facades to evening aperitivo culture in charming piazzas. Every neighborhood presents new angles to capture and flavors to savor.
Ultimately, your interests and priorities will dictate the duration of your stay in Florence. For this itinerary, we’ll focus on making the most of a weekend visit, ensuring you experience the essential highlights while still having time to soak in the unique Florentine atmosphere. So, lace up your walking shoes, adjust your camera strap, and prepare to explore this magnificent Renaissance city!
Best Time to Visit Florence

Timing is crucial when planning your weekend in Florence. From my years living there and numerous return visits, I can tell you that avoiding peak season is worth considering.
The best time to explore Florence is during the shoulder season, which typically runs from April to June and September to October. These months bring pleasantly warm days, consistently blue skies, and comfortable temperatures, perfect for walking tours and outdoor dining.
The golden Mediterranean light during these periods also creates ideal conditions for photography, highlighting the warm terracotta and ochre tones of Florentine architecture.
During shoulder season, you can take advantage of:
- Less crowded museums and attractions (shorter wait times)
- More reasonable accommodation rates
- Pleasant temperatures for walking (65-80°F/18-27°C)
- Authentic local experiences with fewer tourist crowds
I’ve found late spring, specifically May, particularly magical in Florence. The city comes alive with flowers in bloom, and you’ll encounter Instagram-worthy scenes at nearly every turn. The historic Iris and Rose Gardens display stunning floral arrays, and restaurant terraces throughout the city fill with locals enjoying the perfect weather.
With daytime highs averaging around 75°F (24°C), it’s ideal for spending time outdoors, though you should still bring a light jacket for cooler evenings when temperatures can drop to around 55°F (13°C).
Summer crowds swell dramatically during the peak season of July and August. Although the city bathes in gorgeous sunlight, the intense heat (often exceeding 90°F/32°C) and overwhelming tourist numbers can detract from your experience.
Florence’s winter months offer unique charm, but aren’t my first recommendation for a weekend visit. While flights and hotels are more affordable, and Christmas markets create a festive atmosphere, the weather is typically drizzly and rainy.
The shorter daylight hours also limit sightseeing time. However, if you’re seeking a more budget-friendly trip and don’t mind the possibility of rain, winter can provide a more intimate experience with the city’s cultural treasures.
To balance pleasant weather and manageable crowds for your perfect weekend in Florence, the shoulder seasons in spring and fall remain your best options.
How to Get to Florence
By Plane

Florence’s main airport, Amerigo Vespucci (FLR), welcomes flights from various international and domestic locations. Major airlines often have direct flights to Florence, making your travel experience seamless. If you’re flying from a city without a direct connection, consider landing at Pisa Airport (PSA), better connected internationally and just a 1-hour train ride from Florence.
From Florence Airport, you can reach the city center by:
- Taxi (approximately €25, 20 minutes)
- Airport shuttle bus to Santa Maria Novella train station (€6, 25 minutes)
- Tram Line T2 (€1.50, 20 minutes)
By Train

Florence is conveniently situated on Italy’s excellent rail network, making train travel both comfortable and scenic. The city’s primary train station, Santa Maria Novella (SMN), is centrally located and connects to major Italian cities with high-speed trains:
- Rome to Florence: 1.5 hours
- Milan to Florence: 1.75 hours
- Venice to Florence: 2 hours
- Naples to Florence: 3 hours
The station is within walking distance of many hotels and major attractions, making it an excellent choice for weekend travelers. Taxis and buses are available outside the station if your accommodation is further away.
By Car
If you prefer the flexibility of a road trip, driving to Florence is possible but comes with challenges. The historic city center has restricted traffic zones (ZTLs) where unauthorized vehicles can receive fines. Most hotels can arrange temporary access permits for check-in and check-out, but you’ll want to park your car for your stay.
Parking options include:
- Fortezza Fiere parking (€20-25 per day)
- Santa Maria Novella Station parking (€25-30 per day)
- Parking Beccaria (€20 per day)
While driving in Florence itself can be challenging, having a car is ideal if you plan to extend your trip to explore the Tuscan countryside and smaller towns at your own pace.
How to Get Around Florence

Florence’s historic center is compact and pedestrian-friendly, making walking the most enjoyable way to experience the city. Most major attractions are within a 20-30 minute walk of each other, and the journey between sights is part of the Florentine experience. Wandering through charming streets, you’ll discover hidden piazzas, local cafés, and architectural details that aren’t in any guidebook.
For longer distances or to save energy, Florence offers several transportation options:
- Public Buses: ATAF buses cover the entire city, with tickets available at tabacchi shops and newsstands (€1.50 for a 90-minute ticket). Bus C1 connects many tourist attractions.
- Trams: Florence’s modern tram system has two lines, with T1 connecting the center with the southwestern suburbs and T2 linking the airport to the center.
- Taxis: Available at designated taxi stands or by phone (not typically hailed on the street). Major taxi stands are at the train station, Duomo, and Santa Croce. Expect to pay €10-15 for trips within the center.
- Bicycles: Several rental shops offer bikes for around €15 per day. The flat terrain of central Florence makes cycling a pleasant option, especially along the Arno River paths.
For a weekend visit, I recommend the Firenze Card (€85). This card provides entry to major museums and allows you to skip long lines—an invaluable time-saver for a short trip. The card includes public transportation and is valid for 72 hours from the first use.
My tip for exploring Florence efficiently is to group attractions by neighborhood. This approach minimizes travel time and allows you to experience each district’s unique character. Our two-day itinerary follows this neighborhood-based strategy, ensuring you make the most of your weekend in this magnificent Renaissance city.
Two-Day Florence Itinerary

Florence, the cradle of the Renaissance, beckons you with its iconic landmarks, timeless beauty, and exquisite dining. This two-day itinerary will guide you through the city’s must-see attractions, ensuring a memorable trip filled with art, history, and culture.
TL;DR Best Things to Do with Two Days in Florence

Day 1:
- Visit the breathtaking Duomo complex, including Florence Cathedral (Santa Maria del Fiore), Brunelleschi’s dome, the Baptistery with its bronze Gates of Paradise, and Giotto’s Bell Tower
- Experience Mercato Centrale for lunch with authentic Tuscan delicacies
- Tour the Accademia Gallery to admire Michelangelo’s David
- Enjoy a refreshing gelato at Piazza della Repubblica
- Savor an authentic Tuscan dinner at a local trattoria
Day 2:
- Begin at the Uffizi Gallery to view Renaissance masterpieces by Botticelli, Leonardo da Vinci, and Michelangelo
- Have lunch at Gustapanino, a beloved local eatery
- Cross the historic Ponte Vecchio, Florence’s oldest bridge, lined with jewelers’ shops
- Explore the Oltrarno district, including Palazzo Pitti and the beautiful Boboli Gardens
- Watch the sunset from Piazzale Michelangelo for panoramic views of Florence
- Visit Santa Croce and enjoy dinner with a view
The beauty of this itinerary is that most attractions are within walking distance, allowing you to experience the city’s charm as you move between destinations. Let’s explore each day in more detail.
Florence Itinerary Day 1
Morning: The Duomo Complex

Begin your Florence adventure at the city’s heart: the magnificent Duomo Complex. As you approach Piazza del Duomo, the sheer scale and beauty of Florence Cathedral (Santa Maria del Fiore) will take your breath away.
With its distinctive red-tiled dome designed by Filippo Brunelleschi, this architectural marvel dominates the skyline and represents the pinnacle of Renaissance engineering.

Purchase a combined ticket for the entire complex (around €30) and begin your exploration:
- Florence Cathedral: Step inside the vast interior, admiring the intricate marble floor and Vasari’s Last Judgment fresco inside the dome. The cathedral’s austere Gothic interior intentionally contrasts with its elaborate exterior, highlighting the building’s spiritual purpose.
- Brunelleschi’s Dome: If you’re feeling energetic, climb the 463 steps to the top of the dome for panoramic city views. As you ascend, you’ll get an up-close look at Giorgio Vasari’s “The Last Judgment” frescoes inside the dome. The innovative double-shell construction technique was revolutionary when built in the 15th century.
- Baptistery of San Giovanni: Across from the cathedral, this octagonal building showcases classic Florentine Romanesque architecture. The highlight is Lorenzo Ghiberti’s eastern bronze doors, which Michelangelo dubbed the “Gates of Paradise” for their exquisite Biblical relief panels.
- Giotto’s Bell Tower: For alternative city views and fewer crowds than the dome, climb the 414 steps of this elegant Gothic campanile. Its multicolored marble exterior features beautiful sculptural reliefs depicting human activities and Renaissance innovations.
Pro Tip: To avoid long lines, reserve tickets online in advance, especially for dome access, which requires a timed entry. Arrive early (before 9:00 AM) to beat the peak crowds. If you have limited time or energy, prioritize either the dome or bell tower climb, not both.
Lunch: Mercato Centrale

After your morning exploration, walk about 10 minutes north to Mercato Centrale, Florence’s historic food market. This two-story iron and glass structure, dating to 1874, perfectly introduces Tuscan cuisine.
The ground floor hosts traditional food vendors selling fresh ingredients, while the recently renovated upper floor features food stalls where you can sample prepared dishes. Wander through the market, admiring local products like Tuscan cheeses, cured meats, olive oils, and fresh pasta before heading upstairs for lunch.
For an authentic Tuscan lunch experience, try:
- Lampredotto sandwich – a traditional Florentine street food made from slow-cooked cow’s stomach (more delicious than it sounds!)
- Fresh pasta with seasonal truffle or wild boar ragù
- Artisanal cheeses and salumi with Tuscan bread
- A glass of Chianti wine from the nearby hills
The market’s bustling atmosphere provides insight into local food culture and a chance to rest your feet before the afternoon’s activities.
Mid-Afternoon: Palazzo Vecchio & Accademia Gallery

Fueled by your delicious lunch, walk about 15 minutes south to Piazza della Signoria, the political heart of Renaissance Florence. This L-shaped square hosts impressive outdoor sculptures, including a copy of Michelangelo’s David and the imposing Fountain of Neptune.
The square is dominated by Palazzo Vecchio, Florence’s fortress-like town hall crowned by its distinctive crenellated tower. If time permits, you can briefly visit its ornate interior, including the Hall of the Five Hundred with massive battle scene frescoes by Vasari.
Next, take a 10-minute walk northeast to the Accademia Gallery, home to Michelangelo’s original David statue. While smaller than the Uffizi, the Accademia deserves at least 60-90 minutes to fully appreciate its treasures:
- Michelangelo’s David: The 17-foot marble masterpiece depicting the Biblical hero before his battle with Goliath. Take time to observe it from multiple angles, noting the perfectly rendered anatomical details, the contrapposto stance, and David’s intense expression of concentration.
- Prisoners/Slaves: Four unfinished sculptures by Michelangelo that seem to struggle to break free from their marble blocks, offering insight into the artist’s working method.
- Musical Instruments Museum: A collection of historic instruments, including early pianos by Bartolomeo Cristofori, the instrument’s inventor.
Pro Tip: Reservations are essential for the Accademia. Consider hiring a guide or using the audio guide to understand David’s profound significance as a symbol of the Florentine Republic and Renaissance ideals.
Pre-Dinner Break: Gelato at Piazza della Repubblica

After admiring Renaissance masterpieces, treat yourself to Italy’s beloved frozen delicacy: gelato. Head to Piazza della Repubblica, a bustling square about 10 minutes from the Accademia. This elegant piazza marks the site of the ancient Roman forum and features a grand arch and historic carousel.
Several excellent gelaterias surround the square, but for authentic artisanal gelato, look for signs indicating “gelato artigianale” (handmade) and natural colors (pistachio should be pale green, not bright). Popular flavors include:
- Stracciatella (chocolate chip)
- Pistacchio (pistachio)
- Nocciola (hazelnut)
- Fragola (strawberry, seasonal)
- Bacio (chocolate-hazelnut, named after the famous Italian chocolate)
Find a seat on a bench or along the square’s edge to enjoy your gelato while people-watching in this lively space where locals and visitors converge.
Dinner: Authentic Tuscan Trattoria

Experience traditional Tuscan cuisine at a local trattoria or osteria as evening falls. To avoid tourist traps, look for restaurants a few blocks away from major attractions. The menus are in Italian first (with translations), and locals make up a significant portion of the clientele.
For an authentic Florentine dinner, consider these classic dishes:
- Pappardelle al Cinghiale: Wide ribbon pasta with wild boar ragù
- Ribollita: Hearty bread and vegetable soup, a Tuscan peasant classic
- Bistecca alla Fiorentina: The famous T-bone steak, served rare and priced by weight (typically shared)
- Fagioli all’Uccelletto: White beans in tomato sauce with sage
Pair your meal with a bottle of Chianti Classico or another Tuscan wine, and finish with cantucci (almond biscotti) dipped in Vin Santo dessert wine.
Recommended authentic trattorias include Trattoria Sostanza, Osteria Santo Spirito, or Il Latini, though reservations are advisable even for weekday evenings.
See Related: Best Tours in Italy: Food, Walking & Bike Tours
Florence Itinerary Day 2
Morning: Uffizi Gallery & Bargello Museum

Begin your second day with an early start at the world-renowned Uffizi Gallery. This massive U-shaped palace, built in the 16th century for Florentine bureaucratic offices (hence the name “Uffizi,” meaning “offices”), now houses the world’s greatest collection of Renaissance art.
Enter as close to opening time (8:15 AM) as possible, even with advance reservations, to experience the galleries before they become crowded. Plan to spend about 2-3 hours focusing on the highlights:
- Botticelli Room: Housing “The Birth of Venus” and “Primavera,” iconic works embodying Renaissance humanist ideals and Classical mythology
- Leonardo da Vinci’s “Annunciation”: An early masterpiece showcasing his revolutionary techniques
- Michelangelo’s “Doni Tondo”: His only completed panel painting
- Raphael’s portraits: Including “Portrait of Pope Leo X with Cardinals”
- Titian’s “Venus of Urbino”: A sensual masterpiece that influenced generations of painters
- Caravaggio’s “Medusa”: A dramatic example of Baroque intensity
Don’t miss the corridor views of the Arno River and Ponte Vecchio from the gallery windows, offering perfect photo opportunities. With its decorated ceilings and architectural details, the building itself is worth admiring.

After exploring the Uffizi, walk 5 minutes to the Bargello Museum. This former fortress and prison now houses Italy’s premier sculpture collection, perfectly complementing the paintings you’ve just seen. Highlights include:
- Donatello’s bronze “David,” the first freestanding nude male sculpture since antiquity
- Michelangelo’s “Bacchus” and “Pitti Tondo”
- Cellini’s intricate bronze works
- Giambologna’s gravity-defying “Mercury”
The Bargello receives far fewer visitors than Florence’s other museums, offering a more relaxed experience to appreciate these masterpieces up close. The medieval courtyard with its open staircase is particularly atmospheric.
Afternoon & Lunch: Ponte Vecchio and South of the Arno River
For the afternoon, you’ll explore the area south of the Arno, known as Oltrarno (“beyond the Arno”), offering a more authentic glimpse of Florentine life. Structure this section based on your hunger and energy after the museum visits.
Ponte Vecchio

From the Bargello, walk 10 minutes southwest to reach the iconic Ponte Vecchio, Florence’s oldest bridge and one of the few medieval merchant bridges still standing in Europe. Originally home to butchers and tanners, the bridge now houses goldsmiths and jewelers in shops that hang precariously over the water.
Take your time strolling across this historic structure, pausing to admire views of the Arno River in both directions. Above the shops runs the Vasari Corridor, a private elevated passageway built for the Medici to travel between their offices (Uffizi) and residence (Palazzo Pitti) without mingling with commoners.
The bridge provides excellent photo opportunities, especially from the middle section, where you can frame shots of the river with Florence’s buildings reflected in the water.
Lunch at Gustapanino

After crossing Ponte Vecchio, continue to Piazza Santo Spirito for lunch at Gustapanino. This charming, family-run eatery serves excellent panini, pasta dishes, and local specialties using fresh seasonal ingredients. It’s a favorite with locals rather than tourists, offering authentic flavors at reasonable prices.
The outdoor seating on this lively piazza provides excellent people-watching opportunities in one of Florence’s most authentic neighborhoods. Even if you’re not hungry, it’s worth stopping for a refreshing beer or glass of wine while absorbing the local atmosphere.
Palazzo Pitti and Boboli Gardens

After lunch, walk 10 minutes to the imposing Palazzo Pitti, the largest palace in Florence. Built for banker Luca Pitti in the 15th century and later purchased by the Medici family, this massive Renaissance building now houses several museums:
- Palatine Gallery: Displaying the Medici’s private art collection, including works by Raphael, Titian, and Rubens in sumptuous rooms with their original decoration
- Royal Apartments: Showcasing the lavish living quarters of the Medici and later ruling families
- Costume Gallery: Housing historic clothing and accessories
- Modern Art Gallery: Featuring Italian paintings and sculptures from the late 18th to early 20th centuries
Behind the palace are the magnificent Boboli Gardens, one of Europe’s earliest formal gardens and the model for European royal parks. This expansive green space offers welcome relief from urban sightseeing with:
- Renaissance statuary and fountains amid carefully manicured hedges
- The whimsical Grotta Grande, an artificial cave with strange mannerist sculptures
- An Egyptian obelisk in a Roman basin
- Panoramic views of Florence from the upper terraces
Spend 1-2 hours exploring the palace and gardens, which provide insight into how Florence’s elite lived during the Renaissance and beyond. The gardens are refreshing on hot afternoons, with shady paths and cool fountains.
Sunset: Piazzale Michelangelo

As the afternoon transitions to evening, go to Piazzale Michelangelo for Florence’s most spectacular panoramic view. This hilltop terrace offers an unrivaled vista of the entire city, with its red-tiled roofs punctuated by the cathedral’s majestic dome and the Palazzo Vecchio’s tower.
From Boboli Gardens, it’s about a 20-minute walk east along Via di San Leonardo and upstairs to the piazza. Alternatively, you can take bus 12 or 13 from the city center. For the best experience, time your visit to arrive about 30-45 minutes before sunset.
The plaza features a bronze copy of Michelangelo’s David, but the real star is the view. Watch as the setting sun bathes the city in golden light, gradually turning the stone buildings pink and amber. This magical transformation of Florence’s skyline creates perfect photo opportunities and memorable moments.
Consider bringing a bottle of Tuscan wine and plastic cups to enjoy while watching the sunset. Several cafés and a restaurant at the piazza also offer drinks and snacks with a view, though at premium prices.
Evening: Santa Croce & Dinner

After sunset, descend from Piazzale Michelangelo and cross over the Arno to visit Santa Croce basilica. While the interior will be closed by evening, the facade will be beautifully illuminated, and the piazza in front will come alive, with locals and visitors enjoying the evening atmosphere.
This Gothic church serves as Florence’s version of Westminster Abbey, housing the tombs of Italy’s most illustrious figures, including Michelangelo, Galileo, Machiavelli, and the composer Rossini. Even from outside, its distinctive white and green marble facade makes for stunning night photography.
For your final dinner in Florence, choose from several excellent restaurants near Santa Croce. For a unique experience with entertainment, consider booking a table at Belcanto. This superb Tuscan restaurant features live music every evening and opera performances on Wednesdays and Saturdays, combining culinary and cultural pleasures.
Alternatively, wander the streets around Santa Croce to find your hidden gem of a restaurant. Look for places with handwritten menus, locals at the tables, and the enticing aromas of authentic Tuscan cooking.
End your evening with a passeggiata (traditional Italian evening stroll) through Florence’s beautifully lit streets and piazzas, savoring your last night in this magnificent Renaissance city.
Extending Your Stay: Day Trips from Florence
Florence is a treasure trove of art, history, and gastronomy that deserves more than a weekend to fully appreciate. If you’re fortunate enough to extend your stay, consider exploring the magnificent Tuscan countryside surrounding the city. Some exceptional day trips showcase the region’s diverse beauty and cultural heritage.
Take a Day Trip to Siena

Just 50 miles south of Florence, Siena offers a perfectly preserved medieval cityscape that contrasts beautifully with Florence’s Renaissance character. This UNESCO World Heritage site is built across seven hills, with distinctive red-brick buildings and winding streets converging on the magnificent shell-shaped Piazza del Campo.
While in Siena, don’t miss:
- Piazza del Campo: The unique sloping main square where the famous Palio horse race takes place twice yearly (July 2 and August 16)
- Torre del Mangia: Climb this 400-foot tower for breathtaking views of the city and the surrounding countryside
- Siena Cathedral: A masterpiece of Italian Gothic architecture with extraordinary marble inlay floors, sculptures by Donatello and Michelangelo, and frescoes by Pinturicchio
- Museo Civico: Housing Simone Martini’s “Maestà” and Ambrogio Lorenzetti’s “Allegory of Good and Bad Government” fresco cycle
Reaching Siena is simple via direct bus (faster than train) from Florence’s SITA bus station near Santa Maria Novella, which takes about 1 hour and 15 minutes.
Visit San Gimignano

Often called the “Manhattan of the Middle Ages,” San Gimignano’s distinctive skyline of 14 preserved medieval towers (out of an original 72) makes it instantly recognizable. This small walled town perched on a hill offers a remarkable step back in time, with its historic center remaining largely unchanged since the 14th century.
Highlights of San Gimignano include:
- Torre Grossa: The tallest tower, offering panoramic views of the town and surrounding Tuscan landscape
- Collegiate Church: Featuring well-preserved 14th-century frescoes depicting scenes from the Old and New Testaments
- Piazza della Cisterna: A triangular square with an octagonal well at its center, surrounded by medieval palaces
- Award-winning gelato: San Gimignano is home to Gelateria Dondoli, winner of multiple world championships
- Vernaccia di San Gimignano: Sample this distinctive white wine that has been produced here since the Renaissance
San Gimignano can be reached by bus from Florence with a change in Poggibonsi, or more conveniently through organized tours that often combine with other Tuscan towns.
Explore Charming Pienza

Pienza represents the ideal Renaissance city, created when Pope Pius II decided to transform his humble birthplace into a utopian urban center in the 15th century. This UNESCO World Heritage Site sits atop a hill overlooking the stunning Val d’Orcia region, with perfectly proportioned buildings and harmonious public spaces.
Don’t miss these Pienza highlights:
- Piazza Pio II: The perfect Renaissance square, surrounded by the cathedral and noble palaces
- Palazzo Piccolomini: The Pope’s family palace with a hanging garden offering spectacular valley views
- Pienza Cathedral: A unique blend of Gothic and Renaissance styles
- Pecorino di Pienza: Sample the town’s famous sheep’s milk cheese in various stages of aging
While Pienza is farther from Florence than other day trips (about 2 hours by car), its architectural harmony and idyllic setting make it worth the journey. Consider combining it with nearby Montepulciano for a full day of Tuscan exploration.
Relax at Bagni San Fillipo Hot Springs

After days of urban exploration, treat yourself to a rejuvenating experience at the thermal hot springs of Bagni San Filippo. This natural spa destination in southern Tuscany features striking white calcium formations created by mineral-rich waters that have been appreciated since Etruscan and Roman times.
The main attraction is Fosso Bianco (“White Ditch”), where calcified waterfalls form natural pools of varying temperatures perfect for soaking tired muscles. The most impressive formation, called “The White Whale,” creates a magical setting in the wooded valley.
Unlike more commercial thermal baths, Bagni San Filippo’s natural springs are free to access and offer a more authentic experience. The thermal waters, rich in sulfur, calcium, and magnesium, are believed to have therapeutic properties for skin conditions and rheumatic ailments.
For a full experience, combine your natural spring visit with treatments at the town’s thermal spa center or stay overnight at a nearby villa like Podere Val D’Orcia.
Go Wine Tasting in Montepulciano

No Tuscan experience is complete without exploring its famous wine regions, and Montepulciano offers one of the most rewarding wine tours from Florence. This hilltop town combines medieval and Renaissance architecture with world-class wine production, all set against picture-perfect Tuscan countryside.
Montepulciano is famous for its Vino Nobile di Montepulciano, a distinguished DOCG-classified red wine made primarily from Sangiovese grapes. Unlike many wine regions that require driving between vineyards, Montepulciano’s historic cellars are located directly beneath the town, many carved into the tufa rock beneath Renaissance palaces.
Key experiences in Montepulciano include:
- Historic wine cellar tours: Visit ancient underground cellars with massive Slavonian oak casks
- Wine tastings: Sample Vino Nobile di Montepulciano and learn about its production
- Piazza Grande: Explore the main square surrounded by medieval palaces
- San Biagio Church: Admire this Renaissance masterpiece just outside the city walls
- Town walls walk: Enjoy panoramic views of vineyards and the Val d’Orcia and Val di Chiana valleys
While reaching Montepulciano by public transportation requires multiple connections, organized wine tours from Florence provide convenient transportation and expert guidance to maximize your experience.
See Related: Best Wine Regions in Italy to Visit
Where to Stay in Florence

Finding the right accommodation is crucial for maximizing your weekend in Florence. The city offers many options for every budget and travel style, but location is particularly important given your limited time. Here are recommendations for different preferences:
- For convenience and accessibility: The Santa Maria Novella neighborhood near the main train station offers practical accommodations with excellent transport connections. I recommend Hotel Milu, where I stayed for several days. Its central location allowed me to easily access all major attractions while providing modern amenities in a historic building. Read our full Hotel Milu review for a firsthand account of my experience.
- For romantic atmosphere: Hotel Croce Di Malta offers an intimate setting in the heart of Florence, with a rooftop terrace featuring stunning city views. Located within walking distance of the Uffizi Gallery and Ponte Vecchio, this hotel combines convenience with romance. The hotel’s garden courtyard provides a peaceful retreat after busy sightseeing days.
- For luxury travelers: Hotel Regency offers five-star accommodations in a restored 19th-century palazzo. This boutique hotel is located near Piazza d’Azeglio and combines antique furnishings with modern amenities and exceptional service. Its renowned restaurant serves sophisticated Tuscan cuisine, and the elegant garden provides a tranquil setting for breakfast or evening cocktails.
- For apartment-style accommodations: AQA Palace offers spacious apartments in Florence’s historic center. These well-appointed units provide kitchen facilities and separate living areas, perfect for those who prefer more space and independence. The building combines Renaissance architecture with contemporary design, and its central location puts you within easy reach of major attractions.
- For rooftop pool views: During summer months, Plaza Hotel Lucchesi offers a spectacular rooftop pool with panoramic city views. After a day of sightseeing, cool off while admiring the Arno River and Florentine skyline. The hotel’s central location near Santa Croce makes it an excellent base for exploration, while its elegant rooms provide a comfortable retreat.
When choosing accommodations, consider booking properties within the historic center or nearby major attractions. Florence is relatively compact, but staying central will maximize your limited time by reducing transportation needs. Also note that many historic buildings lack elevators, so request a lower floor if mobility is a concern.
Regardless of your accommodation choice, book well in advance, especially during peak season (April-October), when Florence’s popularity means the best properties fill quickly.
See Related: How Much is a Trip to Italy: Average Cost Per Day
Tours of Florence
Consider adding a guided tour to your weekend itinerary for a deeper understanding of Florence’s rich artistic heritage and fascinating history. While independent exploration has merits, knowledgeable local guides can unlock hidden stories and provide context that brings the Renaissance city to life in ways guidebooks cannot.
Walking Tours

Walking through Florence’s historic streets with an expert guide perfectly introduces the city. My love for this city began while strolling these ancient pathways, ultimately inspiring me to create ViaTravelers. A good walking tour will help you get oriented while covering major landmarks and sharing fascinating historical context.
Consider specialized themed tours focusing on particular aspects of Florence’s history, such as Medici power, Dante’s Florence, or Renaissance art innovations. These niche experiences often take you to lesser-known sites while providing deeper insights into specific historical periods or cultural movements.
Museum and Gallery Tours

Florence’s museums contain some of the world’s greatest art treasures, but their significance isn’t always immediately apparent without proper context. Consider taking an expert-led tour for a more meaningful experience at places like the Uffizi or Accademia Gallery.
Art historians can help you appreciate the revolutionary techniques, symbolic meanings, and historical significance of masterpieces like Botticelli’s “Birth of Venus” or Michelangelo’s “David.” A quality private museum tour will navigate efficiently through crowded galleries, highlighting key works while providing engaging commentary.
The Duomo Museum tour is particularly valuable. It helps you understand the architectural and artistic innovations that made Brunelleschi’s dome possible while you view original artifacts like Ghiberti’s bronze Baptistery doors.
Bike Tours
For travelers seeking to cover more ground in less time, bike tours offer an efficient and enjoyable alternative to walking. Florence’s relatively flat historic center is well-suited to cycling, and guided bike tours allow you to visit multiple districts while enjoying commentary through wireless headsets.
Several companies offer bike tours throughout Florence, with options ranging from leisurely two-hour introductory rides to full-day excursions that extend into the surrounding hills. For those who prefer less physical exertion, e-bike tours provide electric assistance while climbing the city’s few hills.
Most bike tours last 2-3 hours and include stops at major landmarks. Guides often share insider recommendations for restaurants and local experiences along the way.
River Cruises
For a unique perspective on Florence, consider experiencing the city from the Arno River. While less common than other tour types, river cruises offer compelling views of historic bridges and riverside palaces from an angle most visitors never see.
Traditional wooden boat (barchetto) tours provide intimate experiences with knowledgeable guides explaining the river’s role in Florence’s development. Many cruises include wine and appetizers or morning coffee service, creating a relaxing interlude between more active sightseeing.
Evening cruises are particularly enchanting, with sunset experiences offering live music and golden hour views of illuminated buildings reflecting in the water.
Food Tours and Cooking Classes
Florence’s culinary heritage is as rich as its artistic traditions, and food-focused experiences provide delicious insights into Tuscan culture. Guided market tours take you through vibrant food halls like Mercato Centrale, introducing you to traditional ingredients while sampling local specialties.
For a more immersive experience, cooking classes teach traditional techniques for creating Tuscan classics like fresh pasta, ribollita soup, or cantucci biscotti. These hands-on experiences typically include wine pairings and a meal, sharing what you’ve prepared.
Wine enthusiasts can enjoy guided tastings at enotecas within the city, or venture into the nearby Chianti region for winery tours and tastings that explore Tuscany’s viticultural heritage.
When Are Places Closed in Florence?

Understanding Florence’s opening and closing schedules is essential for efficient weekend planning. Unlike many tourist destinations with standardized hours, Florence’s museums and attractions follow varied schedules, with specific closure days that can disrupt itineraries if not considered in advance.
Here’s a guide to the major closures you should factor into your planning:
Sunday Closures and Limited Hours
On Sundays, religious sites often prioritize worship over tourism. At Florence Cathedral, visitor access to the main floor is restricted until 1:30 PM to accommodate morning services. The dome climb begins slightly earlier, at 12:45 PM if your weekend includes a Sunday, schedule cathedral visits for the afternoon or plan to visit other attractions during the morning hours.
Monday Closures
Monday is the traditional closing day for many major Florentine museums and galleries. If your weekend extends to Monday, be aware that these significant attractions will be unavailable:
- Uffizi Gallery: Closed all day (reopens Tuesday)
- Accademia Gallery: Closed all day (reopens Tuesday)
- Pitti Palace and Boboli Gardens: Closed all day (reopen Tuesday)
- Villa Bardini: Closed all day (reopens Tuesday)
- San Lorenzo Market & Mercato Centrale: Ground floor vendors closed (upper floor food court remains open)
For Monday visits, focus on open architectural sites, such as the Duomo complex, Ponte Vecchio, and city squares. This is also an excellent day for walking tours or day trips to nearby towns.
Tuesday Limited Hours
The Opera del Duomo Museum houses original artworks and artifacts from the cathedral complex and closes early (at 1:30 PM) on the first Tuesday of each month for staff meetings. If your visit coincides with this day, schedule your Duomo complex visit for early morning.
Thursday Limited Hours
Palazzo Vecchio, Florence’s historic town hall, closes early at 2 PM on Thursdays instead of its usual 7 PM closing time. If you wish to explore this medieval palace on Thursday during your weekend visit, plan to visit in the morning.
Given these varied closure patterns, I recommend structuring your Florence weekend to avoid having major attractions closed on the same day. The two-day itinerary provided earlier is designed with these closure patterns in mind, ensuring you can access key sites when they’re open.
Always verify current operating hours before your trip, as special exhibitions or renovations occasionally modify standard schedules. The official Florence tourism website and museum websites provide the most up-to-date information.
Final Tips for Your Florence Weekend

To make the most of your precious 48 hours in Florence, here are some final practical recommendations:
- Book major attractions in advance: Skip-the-line tickets for the Uffizi, Accademia, and Duomo complex are essential, especially during peak season. The time saved from not standing in long queues will allow you to see more of the city.
- Wear comfortable shoes: Florence is best explored on foot, and you’ll be walking on cobblestone streets and climbing stairs throughout your visit. Fashionable but supportive footwear is a must.
- Carry water and dress appropriately: Summer visitors should bring water bottles (refillable at public fountains throughout the city) and dress in light, breathable fabrics. Remember that churches require covered shoulders and knees.
- Schedule museum visits for mornings: Arrive when major museums open to experience masterpieces with fewer crowds. Use afternoons for neighborhood exploration when museums tend to be busiest.
- Try local specialties: Don’t miss iconic Florentine dishes like bistecca alla fiorentina (T-bone steak), ribollita (bread and vegetable soup), and pappardelle with wild boar ragù. Food is an integral part of understanding Tuscan culture.
- Take time to wander: While it’s important to see major sites, some of Florence’s most magical moments come from unplanned explorations down quiet side streets and lesser-known piazzas.
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